"" 2023 ICD-10 code for Other Megaloblastic Anemias, not elsewhere classified D53.1 - Health and Fitness Informatics


2023 ICD-10 code for Other Megaloblastic Anemias, not elsewhere classified D53.1


2023 ICD-10-CM Diagnosis Code D53.1:

ICD-10 -10 code D53.1 for other megaloblastic anemia, not elsewhere classified as programmed by World Health Organization (WHO) under the range. Illnesses of the blood and blood-forming organs and some disorders engage the immune system. 

Other Megaloblastiv Anemia, not Elsewhere Classified:

Megaloblastic anemia NOS

Excludes 1: Di Gudlielmo’s disease (C94)

  • D53

Includes: Megaloblastic anemia unresponsive to vitamin folate or B12 therapy 

D53.1 is the American ICD-10-CM version, while other worldwide versions of ICD01 53.1 can be varied and according to the edition of 2023, 53.1 turned effective on October 1, 2022.

Applicable To: Megaloblastic Anemia NOS

The following code(s) above D53.1 comprises annotation back-references valid to 53.1.


  • Diseases of the blood and blood-making organs and some disorders engaging the immune system.


  • Other Nutritional anemia 

Approximate synonyms:

  • Acute megaloblastic anemia
  • Anemia, megaloblastic, acute
  • Anemia, B12 and folate deficiency
  • Megaloblastic anemia
  • Anemia, megaloblastic
  • Refractory megaloblastic anemia
  • Primary malignant neoplasm of the renal pelvis
  • Combined b12 and folate deficiency anemia
  • Anemia, megaloblastic, refractory

Clinical information:

  • A disorder characterized by, megaloblasts, and abnormally large red blood cells called megalocytes or macrocytes.
  • Anemia is associated with damaged DNA synthesis in bone marrow progenitor cells leading to dysfunctional erythrocytes or unusually shaped macrocytic. This condition is usually caused by folate or vitamin B12 insufficiency.
  • A disorder characterized by abnormally large erythrocytes in the bone marrow is called megaloblasts. This condition is generally caused by a deficiency of folate or vitamin B12, while other causes comprise drugs and toxins.   


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