"" What Vitamins Help Restless Leg Syndrome? A complete Guide - Health and Fitness Informatics


What Vitamins Help Restless Leg Syndrome? A complete Guide

Vitamin D, B12, Vitamin B6, and vitamin C are some of the vitamins that have been studied for their potential to help in treating RLS.


RLS or Restless Leg Syndrome also called WED or Willis-Ekbom Disease, is a neurological disorder in which you experience uncomfortable sensations in your legs, this condition often causes an irresistible push to move them. A study stated that 7-10%  people of the USA may have Restless Leg Syndrome, it also mentioned that 80% of this population having this condition also experience periodic limb movement of sleep, leading you to move your leg unconsciously, during sleep. 

This condition may lead to disturbed sleep patterns and harmfully impact daily life. While there is no definitive cure for RLS, certain minerals and vitamins have shown promise in improving its symptoms. In this blog, we'll explore the role of vitamins in managing Restless Leg Syndrome and how they can contribute to better overall well-being.

Association between vitamins and RLS:

Several studies have noted that vitamins play a crucial role in the ease of RLS such as NHS (the United Kingdom’s National Health Service) stated (1 in 5) that pregnant women have symptoms of RLS during their the last trimester. However, currently, researchers don’t understand the accurate cause of this relation.     

Another study that evaluated the efficiency of medical therapies for RLS proposes that vitamins E and C taken alone or as a combination therapy are prone to be effective in the treatment of RLS linked with end-stage renal disease.

Another 2015 study also noted that vitamin D supplements may progress symptoms of RLS. The writer notes that vitamin D deficiency appears to be associated with Restless Leg Syndrome.

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1.     Vitamin D:

Vitamin D, also renowned as a name of the "daylight nutrient," believes a huge part in supporting sound bone health and nerve capability. Investing energy outside and getting regular daylight is an incredible method for helping Vitamin D levels. Moreover, Vitamin D enhancements can be taken under the direction of medical care proficient to guarantee satisfactory admission.

Functions of Vitamin D:

Vitamin D is a fat-soluble vitamin that controls phosphate and calcium absorption. Phosphate is an electrically charged unit that contains the mineral phosphorus.  It works with calcium to make strong teeth and bones. Usually, kidneys remove and filter the excess amount of phosphate from the blood.


  • Vitamin D can assist with
  • Regulating blood sugar levels
  • Maintaining healthy muscles and bones
  • Boosting immunity

A study proposed that vitamin D levels are typically lower in people with Restless Leg Syndrome. Researchers linked lower levels of vitamin D with more serious RLS depression and symptoms also lower sleep quality.    

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Vitamin RDA for adults aged 19 to 70 the upper limit of intake is 100 mcg and the lower limit is 15 mcg (micrograms).  

Side Effects of Vitamin D while taking in high dose:

Following are the side effects id Vitamin D when you take in a high dosage:

  • Confusion
  • Vomiting and nausea
  • Thirst and dehydration
  • Muscle weakness
  • Kidney stones
  • Loss of appetite
  • Excessive urination

Vitamin D Contraindications:

Vitamin D may intermingle with some medicines, including:

  • Certain diuretics
  • Certain steroids
  • Certain weight-loss medications
  • Statins

Vitamin C

Ascorbic acid or vitamin C is a water soluble vitamin that is essential for the repair and growth of cells in the body.

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According to a study, scientists administrated vitamin C directly into the bloodstream of individuals getting dialysis. Outcomes suggest it can have effectively declined dialysis complications including improving sleep quality, itching as well as Restless Leg Syndrome (RLS). 


As the National Institute of Health (NIH) suggested that depending on gender and age, the RDA of vitamin C for adults is 75 to 90 mg (milligrams) daily. 

Another NIH study provides the following guidance regarding the potential side effects and contraindication (a condition in which your health expert don’t suggest certain treatment as it may be harmful for the patient) of vitamin C.

Side Effects:

  • High dosage of vitamin C may cause:
  • Nausea
  • Diarrhea
  • Stomach ramps


Before taking Vitamin C supplements for RLS, it’s better to talk with your health expert if you have certain medical conditions. Because, vitamin C may interferes or interacts with other medicines, such as radiotherapy, cancer treatment and chemotherapy.

 Vitamin B12:

For the production of RBCs and the health of your nerves, Vitamin B12 plays an essential role. A deficit in Vitamin B12 may lead to worsening RLS symptoms and damage the nerves. Including B12-rich foods like fish, meat, dairy products, and fortified cereals in your diet can be beneficial. For those with dietary restrictions or absorption issues, Vitamin B12 supplements may be necessary.

Vitamin E:

Vitamin E is an antioxidant fat-soluble vitamin, present in several foods. Since it can’t produce by the body vitamin E is obtained from dietary sources. Oils, Nuts, vegetables, seeds, and green leafy vegetables are tremendous dietary sources of Vitamin E.

 The NIH Sources stated the following benefits, side effects, contraindications, and RDA of vitamin E.

Benefits of Vitamin E:

  • Vitamin E may assist with
  • Boosting the immune system
  • Dilating blood clots
  • Protecting and slowing cell damage


For people aged 14 years and older than RDA of vitamin E is 15 mg daily. For breastfeeding mothers, the RDA elevated to 19 mg.

Side Effects:

If you take excessive dosage of vitamin E then your health expert suggests it may risks lead to some adverse effects, such as an elevated risk of prostate cancer and bleeding.


It is essential to talk with your health expert before taking the following medicines if you are taking vitamin E for RLS.

  • Antioxidants such as niacin and simvastatin
  • Antiplatelet or anticoagulant
  • Radiation therapy or chemotherapy


Iron deficiency is strongly linked with Restless Leg Syndrome. Iron assists with the production of dopamine ( a neurotransmitter) that plays an essential role in controlling movement and sensations. Including iron-rich foods like leafy greens, fortified grains, red meat, and beans, in your diet can help maintain sufficient iron levels. In some cases, iron supplements may be suggested, but it's crucial to consult your health expert before starting any supplementation.


Magnesium is a mineral that supports muscle relaxation and function. Research suggests that magnesium deficiency may cause RLS symptoms. Consuming magnesium-rich foods such as seeds, nuts, seeds, leafy vegetables, and whole grains may help. Magnesium supplements, when taken at the proper dosage, may also help in managing RLS.


While vitamins can play an essential role in alleviating Restless Leg Syndrome symptoms, it's crucial to remember that each individual's situation is unique. Before starting supplements and any significant dietary, it's crucial to consult with your health expert or a qualified nutritionist. They can assess your specific requirements, create a personalized plan, and identify any deficiencies to manage RLS effectively.

Furthermore, apart from incorporating these vitamins into your diet, it is essential to uphold a healthy lifestyle by engaging in regular exercise, ensuring sufficient sleep, and effectively managing stress. By doing so, you can effectively manage the symptoms of Restless Leg Syndrome (RLS). Embracing this precise approach empowers you to take constructive measures toward leading a more tranquil and comfortable life. Always make your health and well-being a top priority, and bear in mind that seeking professional guidance is crucial for achieving the most favorable outcomes in dealing with RLS.

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